1Y5A
Dianhydrosugar-based benzamidine, factor Xa specific inhibitor in complex with bovine trypsin mutant
Summary for 1Y5A
| Entry DOI | 10.2210/pdb1y5a/pdb |
| Related | 1Y59 1Y5B 1Y5U |
| Descriptor | Trypsin, cationic, SULFATE ION, CALCIUM ION, ... (7 entities in total) |
| Functional Keywords | hydrolase, serine protease, serine proteinase |
| Biological source | Bos taurus (bovine) |
| Cellular location | Secreted, extracellular space: P00760 |
| Total number of polymer chains | 1 |
| Total formula weight | 24230.23 |
| Authors | Di Fenza, A.,Heine, A.,Klebe, G. (deposition date: 2004-12-02, release date: 2005-12-13, Last modification date: 2021-11-10) |
| Primary citation | Di Fenza, A.,Heine, A.,Koert, U.,Klebe, G. Understanding binding selectivity toward trypsin and factor Xa: the role of aromatic interactions Chemmedchem, 2:297-308, 2007 Cited by PubMed: 17191291DOI: 10.1002/cmdc.200600185 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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