1Y59
Dianhydrosugar-based benzamidine, factor Xa specific inhibitor in complex with bovine trypsin mutant
Summary for 1Y59
Entry DOI | 10.2210/pdb1y59/pdb |
Related | 1Y5A 1Y5B 1Y5U |
Descriptor | Trypsin, cationic, CALCIUM ION, SULFATE ION, ... (7 entities in total) |
Functional Keywords | hydrolase, serine protease, serine proteinase |
Biological source | Bos taurus (bovine) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 24207.22 |
Authors | Di Fenza, A.,Heine, A.,Klebe, G. (deposition date: 2004-12-02, release date: 2005-12-13, Last modification date: 2021-11-10) |
Primary citation | Di Fenza, A.,Heine, A.,Koert, U.,Klebe, G. Understanding binding selectivity toward trypsin and factor Xa: the role of aromatic interactions Chemmedchem, 2:297-308, 2007 Cited by PubMed: 17191291DOI: 10.1002/cmdc.200600185 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
Download full validation report