1XSP
Crystal Structure of human DNA polymerase lambda in complex with nicked DNA and pyrophosphate
Summary for 1XSP
Entry DOI | 10.2210/pdb1xsp/pdb |
Related | 1XSL 1XSN |
Descriptor | 5'-D(*CP*GP*GP*CP*CP*GP*TP*AP*CP*TP*G)-3', 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... (7 entities in total) |
Functional Keywords | dna polymerase lambda, protein-dna complex, helix-hairpin-helix, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q9UGP5 |
Total number of polymer chains | 4 |
Total formula weight | 44382.05 |
Authors | Garcia-Diaz, M.,Bebenek, K.,Krahn, J.M.,Kunkel, T.A.,Pedersen, L.C. (deposition date: 2004-10-19, release date: 2005-01-18, Last modification date: 2024-02-14) |
Primary citation | Garcia-Diaz, M.,Bebenek, K.,Krahn, J.M.,Kunkel, T.A.,Pedersen, L.C. A closed conformation for the Pol lambda catalytic cycle. Nat.Struct.Mol.Biol., 12:97-98, 2005 Cited by PubMed: 15608652DOI: 10.1038/nsmb876 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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