1XLX
Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Cilomilast
Summary for 1XLX
Entry DOI | 10.2210/pdb1xlx/pdb |
Descriptor | cAMP-specific 3',5'-cyclic phosphodiesterase 4B, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | pde4b, cilomilast, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 92328.93 |
Authors | Card, G.L.,England, B.P.,Suzuki, Y.,Fong, D.,Powell, B.,Lee, B.,Luu, C.,Tabrizizad, M.,Gillette, S.,Ibrahim, P.N.,Artis, D.R.,Bollag, G.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Zhang, K.Y.J. (deposition date: 2004-09-30, release date: 2004-12-14, Last modification date: 2011-07-13) |
Primary citation | Card, G.L.,England, B.P.,Suzuki, Y.,Fong, D.,Powell, B.,Lee, B.,Luu, C.,Tabrizizad, M.,Gillette, S.,Ibrahim, P.N.,Artis, D.R.,Bollag, G.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Zhang, K.Y.J. Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases. Structure, 12:2233-2247, 2004 Cited by PubMed: 15576036DOI: 10.1016/j.str.2004.10.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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