1XLX
Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Cilomilast
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | polymer | 398 | 45731.3 | 2 | UniProt (Q07343) Pfam (PF00233) In PDB | Homo sapiens (human) | DPDE4, PDE32 |
2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A, B | CILOMILAST | non-polymer | 343.4 | 2 | Chemie (CIO) | |||
5 | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A, B: 152 - 528 (UniProt: Q07343)
PDB | External Database | Details |
---|---|---|
Met 131 | - | CLONING ARTIFACT |
Gly 132 | - | CLONING ARTIFACT |
Ser 133 | - | CLONING ARTIFACT |
Ser 134 | - | CLONING ARTIFACT |
His 135 | - | CLONING ARTIFACT |
His 136 | - | CLONING ARTIFACT |
His 137 | - | CLONING ARTIFACT |
His 138 | - | CLONING ARTIFACT |
His 139 | - | CLONING ARTIFACT |
His 140 | - | CLONING ARTIFACT |
Ser 141 | - | CLONING ARTIFACT |
Ser 142 | - | CLONING ARTIFACT |
Gly 143 | - | CLONING ARTIFACT |
Leu 144 | - | CLONING ARTIFACT |
Val 145 | - | CLONING ARTIFACT |
Pro 146 | - | CLONING ARTIFACT |
Arg 147 | - | CLONING ARTIFACT |
Gly 148 | - | CLONING ARTIFACT |
Ser 149 | - | CLONING ARTIFACT |
His 150 | - | CLONING ARTIFACT |
Met 151 | - | CLONING ARTIFACT |
Cme 194 | Cys 366 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 91462.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 866.3 | |
All* | Total formula weight | 92328.9 |