1WPL
Crystal structure of the inhibitory form of rat GTP cyclohydrolase I/GFRP complex
Summary for 1WPL
Entry DOI | 10.2210/pdb1wpl/pdb |
Related | 1is7 |
Descriptor | GTP cyclohydrolase I, GTP cyclohydrolase I feedback regulatory protein, ZINC ION, ... (7 entities in total) |
Functional Keywords | enzyme-regulatory protein complex, hydrolase-protein binding complex, hydrolase/protein binding |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cytoplasm (By similarity): P22288 Nucleus (By similarity): P70552 |
Total number of polymer chains | 20 |
Total formula weight | 360884.82 |
Authors | Maita, N.,Hatakeyama, K.,Okada, K.,Hakoshima, T. (deposition date: 2004-09-08, release date: 2004-09-28, Last modification date: 2023-10-25) |
Primary citation | Maita, N.,Hatakeyama, K.,Okada, K.,Hakoshima, T. Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein J.Biol.Chem., 279:51534-51540, 2004 Cited by PubMed: 15448133DOI: 10.1074/jbc.M409440200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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