1W8B

Factor7 - 413 complex

Summary for 1W8B

Entry DOI	10.2210/pdb1w8b/pdb
Related	1BF9 1CVW 1DAN 1DVA 1F7E 1F7M 1FAK 1FF7 1FFM 1J9C 1JBU 1KLI 1KLJ 1NL8 1QFK 1W0Y 1W2K 1W7X
Descriptor	BLOOD COAGULATION FACTOR VIIA, CALCIUM ION, (S)-[(R)-2-(4-BENZYLOXY-3-METHOXY-PHENYL)-2-(4-CARBAMIMIDOYL-PHENYLAMINO)-ACETYLAMINO]-PHENYL-ACETIC ACID, ... (5 entities in total)
Functional Keywords	serine protease, coagulation, enzyme complex, hydrolase
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Secreted: P08709 P08709
Total number of polymer chains	2
Total formula weight	34954.04
Authors	Ackermann, J.,Alig, L.,Banner, D.W.,Boehm, H.-J.,Groebke-Zbinden, K.,Hilpert, K.,Lave, T.,Kuehne, H.,Obst-Sander, U.,Riederer, M.A.,Stahl, M.,Tschopp, T.B.,Weber, L.,Wessel, H.P. (deposition date: 2004-09-17, release date: 2005-10-25, Last modification date: 2023-12-13)
Primary citation	Groebke-Zbinden, K.,Obst-Sander, U.,Hilpert, K.,Kuehne, H.,Banner, D.W.,Boehm, H.-J.,Stahl, M.,Ackermann, J.,Alig, L.,Weber, L.,Wessel, H.P.,Riederer, M.A.,Tschopp, T.B.,Lave, T. Selective and Orally Bioavailable Phenylglycine Tissue Factor/Factor Viia Inhibitors Bioorg.Med.Chem.Lett., 15:5344-, 2005 Cited by PubMed: 16213138 DOI: 10.1016/J.BMCL.2005.04.079 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation