1W1I

Crystal structure of dipeptidyl peptidase IV (DPPIV or CD26) in complex with adenosine deaminase

Summary for 1W1I

• Entry DOI: 10.2210/pdb1w1i/pdb
• Related: 1J2E 1KRM 1N1M 1NDV 1NDW 1NDY 1NDZ 1NU6 1NU8 1PFQ
• Descriptor: DIPEPTIDYL PEPTIDASE IV, ADENOSINE DEAMINASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: hydrolase, hydrolase-complex, dipetidyl peptidase iv, dppiv, cd26, alpha/beta-hydrolase fold, beta-propeller fold, protein-protein complex, adenosine deaminase, ada, serine protease, aminopeptidase
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 8
• Total formula weight: 511951.93

Authors

Weihofen, W.A.,Liu, J.,Reutter, W.,Saenger, W.,Fan, H. (deposition date: 2004-06-22, release date: 2004-09-02, Last modification date: 2023-12-13)

• Primary citation: Weihofen, W.A.,Liu, J.,Reutter, W.,Saenger, W.,Fan, H.; Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface.; J. Biol. Chem., 279:43330-43335, 2004; PubMed: 15213224; DOI: 10.1074/jbc.M405001200

Experimental method

X-RAY DIFFRACTION (3.03 Å)