1NU8

Crystal structure of human dipeptidyl peptidase IV (DPP-IV) in complex with Diprotin A (IPI)

Summary for 1NU8

• Entry DOI: 10.2210/pdb1nu8/pdb
• Related: 1NU6
• Descriptor: Dipeptidyl peptidase IV, 3-mer peptide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: b-barrel, alpha/beta hydrolase fold, exopeptidase, diprotin a, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 171036.34

Authors

Thoma, R.,Loeffler, B.,Stihle, M.,Huber, W.,Ruf, A.,Hennig, M. (deposition date: 2003-01-31, release date: 2003-08-26, Last modification date: 2020-07-29)

• Primary citation: Thoma, R.,Loeffler, B.,Stihle, M.,Huber, W.,Ruf, A.,Hennig, M.; Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV.; Structure, 11:947-959, 2003; PubMed: 12906826; DOI: 10.1016/S0969-2126(03)00160-6

Experimental method

X-RAY DIFFRACTION (2.5 Å)