1W0Y

tf7a_3771 complex

Summary for 1W0Y

Related1BF9 1CVW 1DAN 1DVA 1F7E 1F7M 1FF7 1FFM 1JBU 1KLI 1KLJ 1QFK 1AHW 1BOY 1FAK 1JPS 1TFH 1W2K 2HFT
DescriptorBLOOD COAGULATION FACTOR VIIA, TISSUE FACTOR, 4-(4-BENZYLOXY-2-METHANESULFONYLAMINO-5-METHOXY-BENZYLAMINO)-BENZAMIDINE, ... (9 entities in total)
Functional Keywordsserine protease, hydrolase, blood coagulation, glycoprotein, plasma, vitamin k, calcium-binding, gamma-carboxyglutamic acid, co-factor, coagulation, enzyme complex
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted P08709 P13726
Membrane; Single-pass type I membrane protein P08709
Total number of polymer chains3
Total molecular weight69478.96
Authors
Banner, D.W.,D'Arcy, A.,Groebke-Zbinden, K.,Ackermann, J.,Kirchhofer, D.,Ji, Y.-H.,Tschopp, T.B.,Wallbaum, S.,Weber, L. (deposition date: 2004-05-27, release date: 2005-01-21, Last modification date: 2011-07-13)
Primary citation
Groebke-Zbinden, K.,Banner, D.W.,Ackermann, J.,D'Arcy, A.,Kirchhofer, D.,Ji, Y.-H.,Tschopp, T.B.,Wallbaum, S.,Weber, L.
Design of Selective Phenylglycine Amide Tissue Factor/Factor Viia Inhibitors
Bioorg.Med.Chem.Lett., 15:817-, 2005
PubMed: 15664864 (PDB entries with the same primary citation)
DOI: 10.1016/J.BMCL.2004.10.092
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.242120.2%3.0%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report