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1VAG

Neuronal nitric oxide synthase oxygenase domain complexed with the inhibitor AR-R17477

Summary for 1VAG
Entry DOI10.2210/pdb1vag/pdb
Related1QW4 1QW5 1QW6 1QWC 1VAF
DescriptorNitric-oxide synthase, brain, ZINC ION, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
Functional Keywordsrat nnosoxy complex with ar-r17477, oxidoreductase
Biological sourceRattus norvegicus (Norway rat)
Cellular locationCell membrane, sarcolemma ; Peripheral membrane protein : P29476
Total number of polymer chains1
Total formula weight49873.26
Authors
Fedorov, R.,Vasan, R.,Ghosh, D.K.,Schlichting, I. (deposition date: 2004-02-16, release date: 2004-06-01, Last modification date: 2023-10-25)
Primary citationFedorov, R.,Vasan, R.,Ghosh, D.K.,Schlichting, I.
Structures of nitric oxide synthase isoforms complexed with the inhibitor AR-R17477 suggest a rational basis for specificity and inhibitor design
Proc.Natl.Acad.Sci.USA, 101:5892-5897, 2004
Cited by
PubMed: 15071192
DOI: 10.1073/pnas.0306588101
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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