1V84

Crystal structure of human GlcAT-P in complex with N-acetyllactosamine, Udp, and Mn2+

Summary for 1V84

Entry DOI	10.2210/pdb1v84/pdb
Related	1V82 1V83
Related PRD ID	PRD_900019
Descriptor	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	transferase, glycoprotein, glycocyltransferase, hnk-1 epitope
Biological source	Homo sapiens (human)
Cellular location	Golgi apparatus membrane; Single-pass type II membrane protein: Q9P2W7
Total number of polymer chains	2
Total formula weight	59911.80
Authors	Kakuda, S.,Shiba, T.,Ishiguro, M.,Tagawa, H.,Oka, S.,Kajihara, Y.,Kawasaki, T.,Wakatsuki, S.,Kato, R. (deposition date: 2003-12-27, release date: 2004-05-25, Last modification date: 2023-10-25)
Primary citation	Kakuda, S.,Shiba, T.,Ishiguro, M.,Tagawa, H.,Oka, S.,Kajihara, Y.,Kawasaki, T.,Wakatsuki, S.,Kato, R. Structural Basis for Acceptor Substrate Recognition of a Human Glucuronyltransferase, GlcAT-P, an Enzyme Critical in the Biosynthesis of the Carbohydrate Epitope HNK-1 J.Biol.Chem., 279:22693-22703, 2004 Cited by PubMed: 14993226 DOI: 10.1074/jbc.M400622200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation