1V3V
Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2
Summary for 1V3V
Entry DOI | 10.2210/pdb1v3v/pdb |
Related | 1V3T 1V3U |
Descriptor | leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | rossmann fold, riken structural genomics/proteomics initiative, rsgi, structural genomics, oxidoreductase |
Biological source | Cavia porcellus (domestic guinea pig) |
Cellular location | Cytoplasm (By similarity): Q9EQZ5 |
Total number of polymer chains | 2 |
Total formula weight | 74864.37 |
Authors | Hori, T.,Yokomizo, T.,Ago, H.,Sugahara, M.,Ueno, G.,Yamamoto, M.,Kumasaka, T.,Shimizu, T.,Miyano, M.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2003-11-06, release date: 2004-07-13, Last modification date: 2023-12-27) |
Primary citation | Hori, T.,Yokomizo, T.,Ago, H.,Sugahara, M.,Ueno, G.,Yamamoto, M.,Kumasaka, T.,Shimizu, T.,Miyano, M. Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem., 279:22615-22623, 2004 Cited by PubMed: 15007077DOI: 10.1074/jbc.M312655200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report