1V18
The crystal structure of beta-catenin armadillo repeat complexed with a phosphorylated APC 20mer repeat.
Summary for 1V18
Entry DOI | 10.2210/pdb1v18/pdb |
Related | 1DEB 1DOW 1EMU 1I7W 1I7X 1JPP 1M1E 1M5I 2BCT 3BCT |
Descriptor | BETA-CATENIN, ADENOMATOUS POLYPOSIS COLI (3 entities in total) |
Functional Keywords | signaling protein, signalling complex, wnt signal, beta-catenin degradation complex, cell adhesion, transcription, transcription regulation |
Biological source | MUS MUSCULUS (MOUSE) More |
Cellular location | Cytoplasm: Q02248 Cell junction, adherens junction: P25054 |
Total number of polymer chains | 2 |
Total formula weight | 64258.73 |
Authors | Ha, N.-C.,Weis, W.I. (deposition date: 2004-04-09, release date: 2005-01-12, Last modification date: 2023-12-13) |
Primary citation | Ha, N.-C.,Tonozuka, T.,Stamos, J.L.,Weis, W.I. Mechanism of Phosphorylation-Dependent Binding of Apc to Beta-Catenin and its Role in Beta-Catenin Degradation Mol.Cell, 15:511-, 2004 Cited by PubMed: 15327768DOI: 10.1016/J.MOLCEL.2004.08.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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