1UOO
Prolyl oligopeptidase from porcine brain, S554A mutant with bound peptide ligand GLY-PHE-ARG-PRO
Summary for 1UOO
Entry DOI | 10.2210/pdb1uoo/pdb |
Related | 1E5T 1E8M 1E8N 1H2W 1H2X 1H2Y 1H2Z 1O6F 1O6G 1QFM 1QFS 1UOQ |
Descriptor | PROLYL ENDOPEPTIDASE, PEPTIDE LIGAND GLY-PHE-ARG-PRO, GLYCEROL, ... (4 entities in total) |
Functional Keywords | hydrolase, prolyl oligopeptidase, amnesia, alpha/ beta-hydrolase, beta-propeller, serine protease |
Biological source | SUS SCROFA (PIG) More |
Total number of polymer chains | 2 |
Total formula weight | 81416.99 |
Authors | |
Primary citation | Szeltner, Z.,Rea, D.,Renner, V.,Juliano, L.,Fulop, V.,Polgar, L. Electrostatic Environment at the Active Site of Prolyl Oligopeptidase is Highly Influential During Substrate Binding J.Biol.Chem., 278:48786-, 2003 Cited by PubMed: 14514675DOI: 10.1074/JBC.M309555200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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