1UOQ

PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, S554A MUTANT WITH BOUND PEPTIDE LIGAND GLU-PHE-SER-PRO

Summary for 1UOQ

• Entry DOI: 10.2210/pdb1uoq/pdb
• Related: 1E5T 1E8M 1E8N 1H2W 1H2X 1H2Y 1H2Z 1O6F 1O6G 1QFM 1QFS 1UOO 1UOP
• Descriptor: PROLYL ENDOPEPTIDASE, PEPTIDE LIGAND GLU-PHE-SER-PRO, GLYCEROL, ... (4 entities in total)
• Functional Keywords: hydrolase, prolyl oligopeptidase, amnesia, alpha/ beta-hydrolase, beta-propeller, serine protease
• Biological source: SUS SCROFA (PIG); More
• Cellular location: Cytoplasm: P23687
• Total number of polymer chains: 2
• Total formula weight: 81511.03

Authors

Rea, D.,Fulop, V. (deposition date: 2003-09-22, release date: 2003-10-02, Last modification date: 2023-12-13)

• Primary citation: Szeltner, Z.,Rea, D.,Renner, V.,Juliano, L.,Fulop, V.,Polgar, L.; Electrostatic Environment at the Active Site of Prolyl Oligopeptidase is Highly Influential During Substrate Binding; J.Biol.Chem., 278:48786-, 2003; PubMed: 14514675; DOI: 10.1074/JBC.M309555200

Experimental method

X-RAY DIFFRACTION (2.1 Å)