1TV6
HIV-1 Reverse Transcriptase Complexed with CP-94,707
Summary for 1TV6
Entry DOI | 10.2210/pdb1tv6/pdb |
Related | 3HVT |
Descriptor | reverse transcriptase p66 subunit, reverse transcriptase p51 subunit, 3-[4-(2-METHYL-IMIDAZO[4,5-C]PYRIDIN-1-YL)BENZYL]-3H-BENZOTHIAZOL-2-ONE (3 entities in total) |
Functional Keywords | transferase |
Biological source | Human immunodeficiency virus type 1 BH10 More |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03366 |
Total number of polymer chains | 2 |
Total formula weight | 116260.51 |
Authors | Pata, J.D.,Stirtan, W.G.,Goldstein, S.W.,Steitz, T.A. (deposition date: 2004-06-28, release date: 2004-07-20, Last modification date: 2023-08-23) |
Primary citation | Pata, J.D.,Stirtan, W.G.,Goldstein, S.W.,Steitz, T.A. Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant RTs resistant to other non-nucleoside inhibitors Proc.Natl.Acad.Sci.USA, 101:10548-10553, 2004 Cited by PubMed: 15249669DOI: 10.1073/pnas.0404151101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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