1TN7

Protein Farnesyltransferase Complexed with a TC21 Peptide Substrate and a FPP Analog at 2.3A Resolution

Summary for 1TN7

Entry DOI	10.2210/pdb1tn7/pdb
Related	1D8D 1FPP 1FT1 1N4Q 1QBQ 1TN6 1TN8 1TNB 1TNO 1TNU 1TNY 1TNZ
Descriptor	Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, Fusion protein, ... (7 entities in total)
Functional Keywords	ftase, farnesyltransferase, farnesyl transferase, prenyltransferase, caax, tc21, lipid modification, prenylation, substrate selectivity, transferase
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	3
Total formula weight	94550.86
Authors	Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. (deposition date: 2004-06-11, release date: 2004-11-02, Last modification date: 2023-08-23)
Primary citation	Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J.Mol.Biol., 343:417-433, 2004 Cited by PubMed: 15451670 DOI: 10.1016/j.jmb.2004.08.056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation