1T2A

Crystal structure of human GDP-D-mannose 4,6-dehydratase

Summary for 1T2A

• Entry DOI: 10.2210/pdb1t2a/pdb
• Descriptor: GDP-mannose 4,6 dehydratase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: structural genomics consortium, rossman-fold, short-chain dehydrogenase/reductase, sdr, structural genomics, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 175551.55

Authors

Walker, J.R.,Vedadi, M.,Sharma, S.,Houston, S.,Wasney, G.,Loppnau, P.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Oppermann, U. (deposition date: 2004-04-20, release date: 2004-05-10, Last modification date: 2023-08-23)

• Primary citation: Vedadi, M.,Walker, J.R.,Sharma, S.,Houston, S.,Wasney, G.,Loppnau, P.,Oppermann, U.; Crystal Structure and Biophysical Characterization of Human GDP-D-mannose 4,6-dehydratase; To be Published,

Experimental method

X-RAY DIFFRACTION (1.84 Å)