1SQ0
Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom Resolution
Summary for 1SQ0
Entry DOI | 10.2210/pdb1sq0/pdb |
Related | 1AUQ 1M0Z 1M10 1OOK 1P8V |
Descriptor | Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II], Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin] (3 entities in total) |
Functional Keywords | leucine rich repeat (lrr), right-handed beta-alpha superhelix); integrin a (or i) domain fold, blood clotting |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P04275 Membrane; Single-pass type I membrane protein: P07359 |
Total number of polymer chains | 2 |
Total formula weight | 56550.86 |
Authors | Dumas, J.J.,Kumar, R.,McDonagh, T.,Sullivan, F.,Stahl, M.L.,Somers, W.S.,Mosyak, L. (deposition date: 2004-03-17, release date: 2004-04-13, Last modification date: 2021-10-27) |
Primary citation | Dumas, J.J.,Kumar, R.,McDonagh, T.,Sullivan, F.,Stahl, M.L.,Somers, W.S.,Mosyak, L. Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations J.Biol.Chem., 279:23327-23334, 2004 Cited by PubMed: 15039442DOI: 10.1074/jbc.M401659200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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