1SQ0
Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II] | polymer | 214 | 24466.4 | 1 | UniProt (P04275) Pfam (PF00092) | Homo sapiens (human) | |
| 2 | B (B) | Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin] | polymer | 288 | 32084.5 | 1 | UniProt (P07359) Pfam (PF01462) Pfam (PF13855) | Homo sapiens (human) | |
| 3 | C, D (A, B) | water | water | 18.0 | 318 | Chemie (HOH) |
Sequence modifications
A: 496 - 709 (UniProt: P04275)
B: 1 - 288 (UniProt: P07359)
| PDB | External Database | Details |
|---|---|---|
| Met 496 | Val 1259 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asp 21 | Asn 37 | SEE REMARK 999 |
| Asp 159 | Asn 175 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56550.9 | |
| All* | Total formula weight | 56550.9 |
