1SM3

CRYSTAL STRUCTURE OF THE TUMOR SPECIFIC ANTIBODY SM3 COMPLEX WITH ITS PEPTIDE EPITOPE

Summary for 1SM3

Entry DOI	10.2210/pdb1sm3/pdb
Descriptor	SM3 ANTIBODY, PEPTIDE EPITOPE, CADMIUM ION, ... (6 entities in total)
Functional Keywords	antibody, peptide antigen, antitumor antibody, complex (antibody-peptide epitope), complex (antibody-peptide epitope) complex, complex (antibody/peptide epitope)
Biological source	Mus musculus (house mouse) More
Cellular location	Apical cell membrane; Single-pass type I membrane protein. Isoform 5: Secreted. Isoform 7: Secreted. Isoform 9: Secreted. Mucin-1 subunit beta: Cell membrane: P15941
Total number of polymer chains	3
Total formula weight	48838.30
Authors	Dokurno, P.,Bates, P.A.,Band, H.A.,Stewart, L.M.D.,Lally, J.M.,Burchell, J.M.,Taylor-Papadimitriou, J.,Sternberg, M.J.E.,Snary, D.,Freemont, P.S. (deposition date: 1997-12-23, release date: 1999-03-23, Last modification date: 2023-08-09)
Primary citation	Dokurno, P.,Bates, P.A.,Band, H.A.,Stewart, L.M.,Lally, J.M.,Burchell, J.M.,Taylor-Papadimitriou, J.,Snary, D.,Sternberg, M.J.,Freemont, P.S. Crystal structure at 1.95 A resolution of the breast tumour-specific antibody SM3 complexed with its peptide epitope reveals novel hypervariable loop recognition. J.Mol.Biol., 284:713-728, 1998 Cited by PubMed: 9826510 DOI: 10.1006/jmbi.1998.2209 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation