1SM3
CRYSTAL STRUCTURE OF THE TUMOR SPECIFIC ANTIBODY SM3 COMPLEX WITH ITS PEPTIDE EPITOPE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | SM3 ANTIBODY | polymer | 215 | 23149.6 | 1 | UniProt (P01723) Pfam (PF07686) | Mus musculus (house mouse) | |
| 2 | B (H) | SM3 ANTIBODY | polymer | 218 | 23460.2 | 1 | UniProt (P01801) Pfam (PF07686) | Mus musculus (house mouse) | |
| 3 | C (P) | PEPTIDE EPITOPE | polymer | 13 | 1258.3 | 1 | UniProt (P15941) | ||
| 4 | D, E, F, G, H... (L, H) | CADMIUM ION | non-polymer | 112.4 | 8 | Chemie (CD) | |||
| 5 | L, M (H) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | N, O, P (L, H, P) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
L: 4 - 212 (UniProt: P01723)
H: 2 - 214 (UniProt: P01801)
| PDB | External Database | Details |
|---|---|---|
| Ser 108 | Gln 130 | conflict |
| Glu 109 | Pro 131 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 3 | Lys 3 | conflict |
| Gln 5 | Glu 5 | conflict |
| Leu 20 | Val 20 | conflict |
| Thr 28 | Ala 28 | conflict |
| Asn 31 | Tyr 31 | conflict |
| Lys 43 | Arg 43 | conflict |
| Val 48 | Ile 48 | conflict |
| Leu 52 | Phe 53 | conflict |
| Ala 56 | - | insertion |
| Gly 94 | Arg 99 | conflict |
| Val 95 | Glu 100 | conflict |
| - | Ile 102 | deletion |
| - | Tyr 103 | deletion |
| - | Tyr 104 | deletion |
| Gln 97 | Pro 105 | conflict |
| Thr 108 | Leu 114 | conflict |
| Ser 113 | Ala 119 | conflict |
| Thr 120 | Ser 126 | conflict |
| Asn 129 | Ala 135 | conflict |
| Ala 131 | Gln 137 | conflict |
| Ser 132 | Thr 138 | conflict |
| Gln 133 | Asn 139 | conflict |
| Ala 160 | Ser 166 | conflict |
| Ala 208 | Lys 214 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 47868.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 970.2 | |
| All* | Total formula weight | 48838.3 |
