1SM3

CRYSTAL STRUCTURE OF THE TUMOR SPECIFIC ANTIBODY SM3 COMPLEX WITH ITS PEPTIDE EPITOPE

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0005886	cellular_component	plasma membrane
L	0006955	biological_process	immune response
L	0019814	cellular_component	immunoglobulin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD H 215

Chain	Residue
H	HIS164
H	HOH314
L	HOH346

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD L 213

Chain	Residue
L	HIS42
L	HOH232
L	HOH290
L	HOH292

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD H 216

Chain	Residue
H	HOH285
H	HOH308
L	HIS188
H	GLU191
H	CL219

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD H 217

Chain	Residue
H	HIS58
H	CL220
H	HOH348
H	HOH373

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD H 218

Chain	Residue
H	HOH288
H	HOH289
H	HOH318
L	GLU126

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD L 214

Chain	Residue
L	SER112
L	HIS197
L	HIS200
L	HOH249

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site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD L 215

Chain	Residue
L	ASN52
L	HOH218
L	HOH237
L	HOH255
L	HOH266
L	HOH282

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD L 216

Chain	Residue
L	GLU160
L	HOH242
L	HOH271
L	HOH321

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site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL H 219

Chain	Residue
H	CD216
L	ARG187

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site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL H 220

Chain	Residue
H	HIS58
H	CD217

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR191-HIS197

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