1SI2
Crystal structure of the PAZ domain of human eIF2c1 in complex with a 9-mer siRNA-like duplex of deoxynucleotide overhang
Summary for 1SI2
Entry DOI | 10.2210/pdb1si2/pdb |
Related | 1SI3 |
Descriptor | 5'-R(*CP*GP*UP*GP*AP*CP*U)-D(P*CP*T)-3', Eukaryotic translation initiation factor 2C 1 (3 entities in total) |
Functional Keywords | protein-rna complex, rna interference, double helix, overhang, gene regulation-rna-dna complex, gene regulation/rna/dna |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, P-body: Q9UL18 |
Total number of polymer chains | 2 |
Total formula weight | 19980.71 |
Authors | |
Primary citation | Ma, J.B.,Ye, K.,Patel, D.J. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature, 429:318-322, 2004 Cited by PubMed: 15152257DOI: 10.1038/nature02519 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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