1SI2
Crystal structure of the PAZ domain of human eIF2c1 in complex with a 9-mer siRNA-like duplex of deoxynucleotide overhang
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 5'-R(*CP*GP*UP*GP*AP*CP*U)-D(P*CP*T)-3' | polymer | 9 | 2790.7 | 1 | |||
| 2 | B (A) | Eukaryotic translation initiation factor 2C 1 | polymer | 149 | 17190.0 | 1 | UniProt (Q9UL18) Pfam (PF02170) | Homo sapiens (human) | EIF2C 1, EIF-2C 1, PUTATIVE RNA-BINDING PROTEIN Q99, ARGONAUTE 1 |
| 3 | C, D (B, A) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 225 - 369 (UniProt: Q9UL18)
| PDB | External Database | Details |
|---|---|---|
| Gly 221 | - | cloning artifact |
| Ser 222 | - | cloning artifact |
| His 223 | - | cloning artifact |
| Met 224 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19980.7 | |
| All* | Total formula weight | 19980.7 |
