1S8G

Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, fatty acid bound form

Summary for 1S8G

Entry DOI	10.2210/pdb1s8g/pdb
Related	1S8H 1S8I
Descriptor	Phospholipase A2 homolog, SULFATE ION, LAURIC ACID, ... (5 entities in total)
Functional Keywords	lys49-phospholipase a2, snake venom, myotoxicity, fatty acid bound form, hydrolase, toxin
Biological source	Agkistrodon contortrix laticinctus (broad-banded copperhead)
Cellular location	Secreted: P49121
Total number of polymer chains	1
Total formula weight	14437.87
Authors	Ambrosio, A.L.B.,de Souza, D.H.F.,Nonato, M.C.,Selistre de Araujo, H.S.,Ownby, C.L.,Garratt, R.C. (deposition date: 2004-02-02, release date: 2004-02-10, Last modification date: 2023-08-23)
Primary citation	Ambrosio, A.L.B.,Nonato, M.C.,Selistre de Araujo, H.S.,Arni, R.,Ward, R.J.,Ownby, C.L.,de Souza, D.H.F.,Garratt, R.C. A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change. J.Biol.Chem., 280:7326-7335, 2005 Cited by PubMed: 15596433 DOI: 10.1074/jbc.M410588200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation