1RO9

CRYSTAL STRUCTURES OF THE CATALYTIC DOMAIN OF PHOSPHODIESTERASE 4B2B COMPLEXED WITH 8-Br-AMP

Summary for 1RO9

Related1RO6
DescriptorcAMP-specific 3',5'-cyclic phosphodiesterase 4B, ZINC ION, 8-BROMO-ADENOSINE-5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywordspde, 8-br-amp, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight88017.57
Authors
Xu, R.X.,Rocque, W.J.,Lambert, M.H.,Vanderwall, D.E.,Nolte, R.T. (deposition date: 2003-12-01, release date: 2004-12-07, Last modification date: 2011-11-16)
Primary citation
Xu, R.X.,Rocque, W.J.,Lambert, M.H.,Vanderwall, D.E.,Luther, M.A.,Nolte, R.T.
Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.
J.Mol.Biol., 337:355-365, 2004
PubMed: 15003452 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2004.01.040
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.13 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers110.4%2.0%7.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1ro9.pdb1.gz [60.77 KB])
Coordinate files for Biological unit (1ro9.pdb2.gz [59.15 KB])