1RL8

Crystal structure of the complex of resistant strain of hiv-1 protease(v82a mutant) with ritonavir

Summary for 1RL8

• Entry DOI: 10.2210/pdb1rl8/pdb
• Related: 1HXW 1N49
• Related PRD ID: PRD_001001
• Descriptor: protease RETROPEPSIN, RITONAVIR (3 entities in total)
• Functional Keywords: aspartic protease, aspartic protease-inhibitor complex, resistant strain, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367
• Total number of polymer chains: 2
• Total formula weight: 22100.12

Authors

Rezacova, P.,Brynda, J.,Sedlacek, J.,Konvalinka, J.,Fabry, M.,Horejsi, M. (deposition date: 2003-11-25, release date: 2005-04-19, Last modification date: 2023-08-23)

• Primary citation: Rezacova, P.,Brynda, J.,Sedlacek, J.,Konvalinka, J.,Fabry, M.,Horejsi, M.; Crystal structure of the complex of resistant strain of hiv-1 protease(v82a mutant) with ritonavir; To be Published, 2005

Experimental method

X-RAY DIFFRACTION (2 Å)