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1RL8

Crystal structure of the complex of resistant strain of hiv-1 protease(v82a mutant) with ritonavir

Summary for 1RL8
Entry DOI10.2210/pdb1rl8/pdb
Related1HXW 1N49
Related PRD IDPRD_001001
Descriptorprotease RETROPEPSIN, RITONAVIR (3 entities in total)
Functional Keywordsaspartic protease, aspartic protease-inhibitor complex, resistant strain, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman immunodeficiency virus 1
Cellular locationMatrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367
Total number of polymer chains2
Total formula weight22100.12
Authors
Rezacova, P.,Brynda, J.,Sedlacek, J.,Konvalinka, J.,Fabry, M.,Horejsi, M. (deposition date: 2003-11-25, release date: 2005-04-19, Last modification date: 2023-08-23)
Primary citationRezacova, P.,Brynda, J.,Sedlacek, J.,Konvalinka, J.,Fabry, M.,Horejsi, M.
Crystal structure of the complex of resistant strain of hiv-1 protease(v82a mutant) with ritonavir
To be Published, 2005
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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