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1RC1

Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid

Summary for 1RC1
Entry DOI10.2210/pdb1rc1/pdb
Related1MEJ 1MEO 1NJS 1RBM 1RBQ 1RBY 1RBZ 1RC0
DescriptorPHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE, PHOSPHATE ION, N-{4-4-(2,4-DIAMINO-6-OXO-1,6-DIHYDRO-PYRIMIDIN-5-YL)-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXY-ETHYL)-BUT-2-YL-BENZOYL}-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GLUTAMIC ACID, ... (4 entities in total)
Functional Keywordsprotein-cofactor analogue complex, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight47155.21
Authors
Zhang, Y.,Desharnais, J.,Boger, D.L.,Wilson, I.A. (deposition date: 2003-11-03, release date: 2005-06-14, Last modification date: 2023-08-23)
Primary citationZhang, Y.,Desharnais, J.,Boger, D.L.,Wilson, I.A.
Human GAR Tfase complex structure
To be Published,
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

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