1RC1
Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid
Summary for 1RC1
Entry DOI | 10.2210/pdb1rc1/pdb |
Related | 1MEJ 1MEO 1NJS 1RBM 1RBQ 1RBY 1RBZ 1RC0 |
Descriptor | PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE, PHOSPHATE ION, N-{4-4-(2,4-DIAMINO-6-OXO-1,6-DIHYDRO-PYRIMIDIN-5-YL)-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXY-ETHYL)-BUT-2-YL-BENZOYL}-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GLUTAMIC ACID, ... (4 entities in total) |
Functional Keywords | protein-cofactor analogue complex, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 47155.21 |
Authors | Zhang, Y.,Desharnais, J.,Boger, D.L.,Wilson, I.A. (deposition date: 2003-11-03, release date: 2005-06-14, Last modification date: 2023-08-23) |
Primary citation | Zhang, Y.,Desharnais, J.,Boger, D.L.,Wilson, I.A. Human GAR Tfase complex structure To be Published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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