1RC1
Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | polymer | 209 | 22678.9 | 2 | UniProt (P22102) Pfam (PF00551) | Homo sapiens (human) | GART; GAR transformylase; 5'-phosphoribosylglycinamide transformylase |
| 2 | C, E (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | D, F (A, B) | N-{4-4-(2,4-DIAMINO-6-OXO-1,6-DIHYDRO-PYRIMIDIN-5-YL)-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXY-ETHYL)-BUT-2-YL-BENZOYL}-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GLUTAMIC ACID | non-polymer | 803.7 | 2 | Chemie (KT3) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 203 (UniProt: P22102)
| PDB | External Database | Details |
|---|---|---|
| His 204 | - | expression tag |
| His 205 | - | expression tag |
| His 206 | - | expression tag |
| His 207 | - | expression tag |
| His 208 | - | expression tag |
| His 209 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45357.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1797.3 | |
| All* | Total formula weight | 47155.2 |
