1RC1
Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | polymer | 209 | 22678.9 | 2 | UniProt (P22102) Pfam (PF00551) In PDB | Homo sapiens (human) | GART; GAR transformylase; 5'-phosphoribosylglycinamide transformylase |
2 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
3 | A, B | N-{4-4-(2,4-DIAMINO-6-OXO-1,6-DIHYDRO-PYRIMIDIN-5-YL)-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXY-ETHYL)-BUT-2-YL-BENZOYL}-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GLUTAMIC ACID | non-polymer | 803.7 | 2 | Chemie (KT3) | |||
4 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 203 (UniProt: P22102)
PDB | External Database | Details |
---|---|---|
His 204 | - | expression tag |
His 205 | - | expression tag |
His 206 | - | expression tag |
His 207 | - | expression tag |
His 208 | - | expression tag |
His 209 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 45357.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1797.3 | |
All* | Total formula weight | 47155.2 |