1RC1

Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE	polymer	209	22678.9	2	UniProt (P22102) Pfam (PF00551) In PDB	Homo sapiens (human)	GART; GAR transformylase; 5'-phosphoribosylglycinamide transformylase
2	A, B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
3	A, B	N-{4-4-(2,4-DIAMINO-6-OXO-1,6-DIHYDRO-PYRIMIDIN-5-YL)-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXY-ETHYL)-BUT-2-YL-BENZOYL}-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GLUTAMIC ACID	non-polymer		803.7	2	Chemie (KT3)
4		water	water		18.0	130	Chemie (HOH)

Sequence modifications

A, B: 1 - 203 (UniProt: P22102)

PDB	External Database	Details
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45357.9
Non-Polymers*	Number of molecules	4
	Total formula weight	1797.3
All*	Total formula weight	47155.2

*Water molecules are not included.