1R9M

Crystal Structure of Human Dipeptidyl Peptidase IV at 2.1 Ang. Resolution.

Summary for 1R9M

• Entry DOI: 10.2210/pdb1r9m/pdb
• Related: 1R9N
• Descriptor: Dipeptidyl peptidase IV, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: aminopeptidase, serine protease, glycoprotein, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 349304.56

Authors

Aertgeerts, K.,Ye, S.,Tennant, M.G.,Collins, B.,Rogers, J.,Sang, B.C.,Skene, R.J.,Webb, D.R.,Prasad, G.S. (deposition date: 2003-10-30, release date: 2004-06-29, Last modification date: 2020-07-29)

• Primary citation: Aertgeerts, K.,Ye, S.,Tennant, M.G.,Kraus, M.L.,Rogers, J.,Sang, B.C.,Skene, R.J.,Webb, D.R.,Prasad, G.S.; Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation.; Protein Sci., 13:412-421, 2004; PubMed: 14718659; DOI: 10.1110/ps.03460604

Experimental method

X-RAY DIFFRACTION (2.1 Å)