1R9N
Crystal Structure of human dipeptidyl peptidase IV in complex with a decapeptide (tNPY) at 2.3 Ang. Resolution
Summary for 1R9N
Entry DOI | 10.2210/pdb1r9n/pdb |
Related | 1R9M |
Descriptor | Dipeptidyl peptidase IV, Neuropeptide Y, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | alpha/beta hydrolase, eight-bladed beta propeller, serine protease, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 352425.95 |
Authors | Aertgeerts, K.,Ye, S.,Tennant, M.G.,Collins, B.,Rogers, J.,Sang, B.-C.,Skene, R.,Webb, D.R.,Prasad, G.S. (deposition date: 2003-10-30, release date: 2005-03-29, Last modification date: 2023-08-23) |
Primary citation | Aertgeerts, K.,Ye, S.,Tennant, M.G.,Kraus, M.L.,Rogers, J.,Sang, B.-C.,Skene, R.J.,Webb, D.R.,Prasad, G.S. Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation. Protein Sci., 13:412-421, 2004 Cited by PubMed: 14718659DOI: 10.1110/ps.03460604 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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