1R9N
Crystal Structure of human dipeptidyl peptidase IV in complex with a decapeptide (tNPY) at 2.3 Ang. Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, B, C, D) | Dipeptidyl peptidase IV | polymer | 739 | 85637.8 | 4 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (human) | DPP IV, T-cell activation antigen CD26, TP103, Adenosine deaminase complexing protein-2, ADABP |
| 2 | B, D, F, H (E, F, G, H) | Neuropeptide Y | polymer | 10 | 1104.1 | 4 | UniProt (Q9XSW6) | ||
| 3 | I, J, K, L (I, J, K, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 4 | AA, BA, CA, M, N... (C, D, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 17 | Chemie (NAG) | |||
| 5 | DA, EA, FA, GA, HA... (A, E, B, F, C...) | water | water | 18.0 | 1249 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 39 - 766 (UniProt: P27487)
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | - | cloning artifact |
| Asp 29 | - | cloning artifact |
| Pro 30 | - | cloning artifact |
| Gly 31 | - | cloning artifact |
| Gly 32 | - | cloning artifact |
| Ser 33 | - | cloning artifact |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 346967.8 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3760.5 | |
| All* | Total formula weight | 352425.9 |
