1R9N
Crystal Structure of human dipeptidyl peptidase IV in complex with a decapeptide (tNPY) at 2.3 Ang. Resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Dipeptidyl peptidase IV | polymer | 739 | 85637.8 | 4 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) In PDB | Homo sapiens (human) | DPP IV, T-cell activation antigen CD26, TP103, Adenosine deaminase complexing protein-2, ADABP |
2 | E, F, G, H | Neuropeptide Y | polymer | 10 | 1104.1 | 4 | UniProt (Q9XSW6) In PDB | ||
3 | I, J, K, L | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
4 | C, D, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 17 | Chemie (NAG) | |||
5 | water | water | 18.0 | 1249 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 39 - 766 (UniProt: P27487)
PDB | External Database | Details |
---|---|---|
Ala 28 | - | cloning artifact |
Asp 29 | - | cloning artifact |
Pro 30 | - | cloning artifact |
Gly 31 | - | cloning artifact |
Gly 32 | - | cloning artifact |
Ser 33 | - | cloning artifact |
His 34 | - | expression tag |
His 35 | - | expression tag |
His 36 | - | expression tag |
His 37 | - | expression tag |
His 38 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 346967.8 | |
Branched | Number of molecules | 4 |
Total formula weight | 1697.6 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 3760.5 | |
All* | Total formula weight | 352425.9 |