1R1I

STRUCTURAL ANALYSIS OF NEPRILYSIN WITH VARIOUS SPECIFIC AND POTENT INHIBITORS

Summary for 1R1I

• Entry DOI: 10.2210/pdb1r1i/pdb
• Related: 1DMT 1R1H 1R1J
• Descriptor: Neprilysin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (5 entities in total)
• Functional Keywords: lt1_9, glycoprotein, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type II membrane protein: P08473
• Total number of polymer chains: 1
• Total formula weight: 80635.04

Authors

Oefner, C.,Roques, B.P.,Fournie-Zaluski, M.C.,Dale, G.E. (deposition date: 2003-09-24, release date: 2004-09-28, Last modification date: 2020-07-29)

• Primary citation: Oefner, C.,Roques, B.P.,Fournie-Zaluski, M.C.,Dale, G.E.; Structural analysis of neprilysin with various specific and potent inhibitors.; Acta Crystallogr.,Sect.D, 60:392-396, 2004; PubMed: 14747736; DOI: 10.1107/S0907444903027410

Experimental method

X-RAY DIFFRACTION (2.6 Å)