1QKU
WILD TYPE ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL
Summary for 1QKU
Entry DOI | 10.2210/pdb1qku/pdb |
Related | 1A52 1AKF 1ERE 1ERR 1HCP 1HCQ 1QKM 1QKN 1QKU 3ERD 3ERT |
Descriptor | ESTRADIOL RECEPTOR, ESTRADIOL (3 entities in total) |
Functional Keywords | nuclear receptor, agonism, antagonism, estradiol receptor, steroid, structural proteomics in europe, spine, structural genomics |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Isoform 1: Nucleus . Isoform 3: Nucleus. Nucleus: P03372 |
Total number of polymer chains | 3 |
Total formula weight | 86676.33 |
Authors | Ruff, M.,Gangloff, M.,Eiler, S.,Duclaud, S.,Wurtz, J.M.,Moras, D. (deposition date: 1999-08-05, release date: 2000-08-18, Last modification date: 2024-05-08) |
Primary citation | Gangloff, M.,Ruff, M.,Eiler, S.,Duclaud, S.,Wurtz, J.M.,Moras, D. Crystal structure of a mutant hERalpha ligand-binding domain reveals key structural features for the mechanism of partial agonism. J. Biol. Chem., 276:15059-15065, 2001 Cited by PubMed: 11278577DOI: 10.1074/jbc.M009870200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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