1QHF

YEAST PHOSPHOGLYCERATE MUTASE-3PG COMPLEX STRUCTURE TO 1.7 A

Summary for 1QHF

• Entry DOI: 10.2210/pdb1qhf/pdb
• Descriptor: PROTEIN (PHOSPHOGLYCERATE MUTASE), SULFATE ION, 3-PHOSPHOGLYCERIC ACID, ... (4 entities in total)
• Functional Keywords: transferase (phosphoryl), transferase
• Biological source: Saccharomyces cerevisiae (baker's yeast)
• Total number of polymer chains: 2
• Total formula weight: 54533.66

Authors

Crowhurst, G.,Littlechild, J.,Watson, H.C. (deposition date: 1999-05-13, release date: 1999-06-10, Last modification date: 2023-08-16)

Primary citation

Crowhurst, G.S.,Dalby, A.R.,Isupov, M.N.,Campbell, J.W.,Littlechild, J.A.
Structure of a phosphoglycerate mutase:3-phosphoglyceric acid complex at 1.7 A.
Acta Crystallogr.,Sect.D, 55:1822-1826, 1999

PubMed Abstract: The crystal structure of the tetrameric glycolytic enzyme phosphoglycerate mutase from the yeast Saccharomyces cerevisiae has been determined to 1.7 A resolution in complex with the sugar substrate. The difference map indicates that 3-phosphoglycerate is bound at the base of a 12 A cleft, positioning C2 of the substrate within 3.5 A of the primary catalytic residue, histidine 8.

PubMed: 10531478
DOI: 10.1107/S0907444999009944

Experimental method

X-RAY DIFFRACTION (1.7 Å)