1Q5H

Human dUTP Pyrophosphatase complex with dUDP

Summary for 1Q5H

Entry DOI	10.2210/pdb1q5h/pdb
Descriptor	dUTP pyrophosphatase, MAGNESIUM ION, DEOXYURIDINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	dna repair, enzyme-dna interactions, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Mitochondrion. Isoform 2: Nucleus: P33316
Total number of polymer chains	3
Total formula weight	49921.62
Authors	Mol, C.D.,Harris, J.M.,McIntosh, E.M.,Tainer, J.A. (deposition date: 2003-08-07, release date: 2003-08-19, Last modification date: 2023-08-16)
Primary citation	Mol, C.D.,Harris, J.M.,McIntosh, E.M.,Tainer, J.A. Human dUTP pyrophosphatase: uracil recognition by a Beta hairpin and active sites formed by three separate subunits Structure, 4:1077-1092, 1996 Cited by PubMed: 8805593 DOI: 10.1016/S0969-2126(96)00114-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation