1Q5H
Human dUTP Pyrophosphatase complex with dUDP
Summary for 1Q5H
Entry DOI | 10.2210/pdb1q5h/pdb |
Descriptor | dUTP pyrophosphatase, MAGNESIUM ION, DEOXYURIDINE-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | dna repair, enzyme-dna interactions, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Mitochondrion. Isoform 2: Nucleus: P33316 |
Total number of polymer chains | 3 |
Total formula weight | 49921.62 |
Authors | Mol, C.D.,Harris, J.M.,McIntosh, E.M.,Tainer, J.A. (deposition date: 2003-08-07, release date: 2003-08-19, Last modification date: 2023-08-16) |
Primary citation | Mol, C.D.,Harris, J.M.,McIntosh, E.M.,Tainer, J.A. Human dUTP pyrophosphatase: uracil recognition by a Beta hairpin and active sites formed by three separate subunits Structure, 4:1077-1092, 1996 Cited by PubMed: 8805593DOI: 10.1016/S0969-2126(96)00114-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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