1Q5H
Human dUTP Pyrophosphatase complex with dUDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004170 | molecular_function | dUTP diphosphatase activity |
| A | 0006226 | biological_process | dUMP biosynthetic process |
| A | 0046081 | biological_process | dUTP catabolic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004170 | molecular_function | dUTP diphosphatase activity |
| B | 0006226 | biological_process | dUMP biosynthetic process |
| B | 0046081 | biological_process | dUTP catabolic process |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004170 | molecular_function | dUTP diphosphatase activity |
| C | 0006226 | biological_process | dUMP biosynthetic process |
| C | 0046081 | biological_process | dUTP catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 999 |
| Chain | Residue |
| A | GLU112 |
| A | HOH1012 |
| B | GLU112 |
| C | GLU112 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE DUD A 779 |
| Chain | Residue |
| A | TYR82 |
| A | GLY87 |
| A | HOH1008 |
| A | HOH1043 |
| A | HOH1046 |
| B | GLU129 |
| B | GLY134 |
| B | PHE135 |
| B | GLY136 |
| C | ARG62 |
| C | SER63 |
| C | GLY64 |
| A | ALA75 |
| A | GLY76 |
| A | VAL77 |
| A | ILE78 |
| A | ASP79 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE DUD B 778 |
| Chain | Residue |
| A | ARG62 |
| A | SER63 |
| A | GLY64 |
| B | ALA75 |
| B | GLY76 |
| B | VAL77 |
| B | ILE78 |
| B | ASP79 |
| B | TYR82 |
| B | GLY87 |
| B | HOH801 |
| B | HOH846 |
| C | ARG130 |
| C | GLY134 |
| C | PHE135 |
| C | GLY136 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE DUD C 777 |
| Chain | Residue |
| B | ARG62 |
| B | SER63 |
| B | GLY64 |
| B | ARG105 |
| C | ALA75 |
| C | GLY76 |
| C | VAL77 |
| C | ILE78 |
| C | ASP79 |
| C | TYR82 |
| C | GLY87 |
| C | HOH796 |
| C | HOH814 |
| C | HOH816 |
| C | HOH844 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8805593","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17880943","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1Q5H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HQU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EHW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8805593","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17880943","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1Q5H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HQU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ARA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ARN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EHW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dup |
| Chain | Residue | Details |
| A | ASP81 | |
| A | ASP79 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dup |
| Chain | Residue | Details |
| B | ASP81 | |
| B | ASP79 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dup |
| Chain | Residue | Details |
| C | ASP81 | |
| C | ASP79 |
