1Q3V

Crystal structure of a wild-type Cre recombinase-loxP synapse: phosphotyrosine covalent intermediate

Summary for 1Q3V

Entry DOI	10.2210/pdb1q3v/pdb
Related	1NZB 1OUQ 1Q3U
Descriptor	loxP DNA, Cre recombinase, IODIDE ION, ... (7 entities in total)
Functional Keywords	cre, recombinase, dna, replication-dna complex, replication/dna
Biological source	Enterobacteria phage P1
Total number of polymer chains	10
Total formula weight	202296.25
Authors	Ennifar, E.,Meyer, J.E.W.,Buchholz, F.,Stewart, A.F.,Suck, D. (deposition date: 2003-08-01, release date: 2003-09-16, Last modification date: 2023-08-16)
Primary citation	Ennifar, E.,Meyer, J.E.W.,Buchholz, F.,Stewart, A.F.,Suck, D. Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation Nucleic Acids Res., 31:5449-5460, 2003 Cited by PubMed: 12954782 DOI: 10.1093/nar/gkg732 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.91 Å)

Structure validation