1PWW
Crystal structure of Anthrax Lethal Factor active site mutant protein complexed with an optimised peptide substrate in the presence of zinc.
Summary for 1PWW
| Entry DOI | 10.2210/pdb1pww/pdb |
| Related | 1PQW 1PWP 1PWU 1PWV |
| Descriptor | Lethal factor, LF20, ZINC ION (3 entities in total) |
| Functional Keywords | anthrax toxin, lethal factor (active site mutant), optimised peptide substrate, hydrolase |
| Biological source | Bacillus anthracis More |
| Cellular location | Secreted: P15917 |
| Total number of polymer chains | 4 |
| Total formula weight | 185502.15 |
| Authors | Wong, T.Y.,Schwarzenbacher, R.,Liddington, R.C. (deposition date: 2003-07-02, release date: 2004-01-27, Last modification date: 2023-08-16) |
| Primary citation | Turk, B.E.,Wong, T.Y.,Schwarzenbacher, R.,Jarrell, E.T.,Leppla, S.H.,Collier, R.J.,Liddington, R.C.,Cantley, L.C. The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat.Struct.Mol.Biol., 11:60-66, 2004 Cited by PubMed: 14718924DOI: 10.1038/nsmb708 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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