1PWW
Crystal structure of Anthrax Lethal Factor active site mutant protein complexed with an optimised peptide substrate in the presence of zinc.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lethal factor | polymer | 776 | 90330.8 | 2 | UniProt (P15917) Pfam (PF07737) Pfam (PF09156) | Bacillus anthracis | LF, Anthrax lethal toxin endopeptidase component |
| 2 | C, D (C, D) | LF20 | polymer | 20 | 2354.8 | 2 | |||
| 3 | E, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, B: 1 - 776 (UniProt: P15917)
| PDB | External Database | Details |
|---|---|---|
| Cys 687 | Glu 720 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 185371.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 185502.2 |
