1P22
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity on the SCFbeta-TrCP1 ubiquitin ligase
Summary for 1P22
Entry DOI | 10.2210/pdb1p22/pdb |
Descriptor | F-box/WD-repeat protein 1A, Skp1, Beta-catenin (3 entities in total) |
Functional Keywords | ubiquitination, degradation, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q9Y297 P35222 |
Total number of polymer chains | 3 |
Total formula weight | 69195.61 |
Authors | Wu, G.,Xu, G.,Schulman, B.A.,Jeffrey, P.D.,Harper, J.W.,Pavletich, N.P. (deposition date: 2003-04-14, release date: 2003-07-08, Last modification date: 2011-07-13) |
Primary citation | Wu, G.,Xu, G.,Schulman, B.A.,Jeffrey, P.D.,Harper, J.W.,Pavletich, N.P. Structure of a beta-TrCP1-Skp1-beta-Catenin complex: destruction motif binding and lysine specificity of the SCFbeta-TrCP1 ubiquitin ligase Mol.Cell, 11:1445-1456, 2003 Cited by PubMed: 12820959DOI: 10.1016/S1097-2765(03)00234-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
Download full validation report