1OZ0
CRYSTAL STRUCTURE OF THE HOMODIMERIC BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME AVIAN ATIC IN COMPLEX WITH A MULTISUBSTRATE ADDUCT INHIBITOR BETA-DADF.
Summary for 1OZ0
Entry DOI | 10.2210/pdb1oz0/pdb |
Related | 1G8M 1M9N |
Descriptor | Bifunctional purine biosynthesis protein PURH, POTASSIUM ION, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | homodimer, 2 functional domains, impch domain = alpha/beta/alpha, aicar tfase = 2 alpha/beta/alpha domains, 1 alpha + beta domain, transferase, hydrolase |
Biological source | Gallus gallus (chicken) |
Total number of polymer chains | 2 |
Total formula weight | 135237.58 |
Authors | Wolan, D.W.,Greasley, S.E.,Wall, M.J.,Benkovic, S.J.,Wilson, I.A. (deposition date: 2003-04-07, release date: 2003-09-30, Last modification date: 2023-08-16) |
Primary citation | Wolan, D.W.,Greasley, S.E.,Wall, M.J.,Benkovic, S.J.,Wilson, I.A. Structure of Avian AICAR Transformylase with a Multisubstrate Adduct Inhibitor beta-DADF Identifies the Folate Binding Site. Biochemistry, 42:10904-10914, 2003 Cited by PubMed: 12974624DOI: 10.1021/bi030106h PDB entries with the same primary citation |
Experimental method |
Structure validation
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