1N5Q

Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with dehydrated Sancycline

Summary for 1N5Q

• Entry DOI: 10.2210/pdb1n5q/pdb
• Related: 1LQ9 1N5S 1N5T 1N5V
• Descriptor: ActaVA-Orf6 monooxygenase, HEXAETHYLENE GLYCOL, 4-DIMETHYLAMINO-1,10,11,12-TETRAHYDROXY-3-OXO-3,4,4A,5-TETRAHYDRO-NAPHTHACENE-2-CARBOXYLIC ACID AMIDE, ... (4 entities in total)
• Functional Keywords: monooxygenase, aromatic polyketides, actinorhodin, dihydrokalafungin, sancycline, streptomyces coelicolor, oxidoreductase
• Biological source: Streptomyces coelicolor
• Total number of polymer chains: 2
• Total formula weight: 24635.56

Authors

Sciara, G.,Kendrew, S.G.,Miele, A.E.,Marsh, N.G.,Federici, L.,Malatesta, F.,Schimperna, G.,Savino, C.,Vallone, B. (deposition date: 2002-11-07, release date: 2003-01-14, Last modification date: 2024-02-14)

• Primary citation: Sciara, G.,Kendrew, S.G.,Miele, A.E.,Marsh, N.G.,Federici, L.,Malatesta, F.,Schimperna, G.,Savino, C.,Vallone, B.; The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis; Embo J., 22:205-215, 2003; PubMed: 12514126; DOI: 10.1093/emboj/cdg031

Experimental method

X-RAY DIFFRACTION (1.74 Å)