1MXF
Crystal Structure of Inhibitor Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi
Summary for 1MXF
Entry DOI | 10.2210/pdb1mxf/pdb |
Related | 1E7W 1E92 |
Descriptor | PTERIDINE REDUCTASE 2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, METHOTREXATE, ... (4 entities in total) |
Functional Keywords | sdr topology, protein-inhibitor complex, oxidoreductase |
Biological source | Trypanosoma cruzi |
Total number of polymer chains | 4 |
Total formula weight | 122087.27 |
Authors | Schormann, N.,Pal, B.,Senkovich, O.,Carson, M.,Howard, A.,Smith, C.,Delucas, L.,Chattopadhyay, D. (deposition date: 2002-10-02, release date: 2003-10-14, Last modification date: 2017-10-11) |
Primary citation | Schormann, N.,Pal, B.,Senkovich, O.,Carson, M.,Howard, A.,Smith, C.,Delucas, L.,Chattopadhyay, D. Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor. J.Struct.Biol., 152:64-75, 2005 Cited by PubMed: 16168672DOI: 10.1016/j.jsb.2005.07.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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