Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NDP A 1277 |
| Chain | Residue |
| A | ARG21 |
| A | SER72 |
| A | ASN101 |
| A | ALA102 |
| A | SER103 |
| A | GLU131 |
| A | LEU167 |
| A | CYS168 |
| A | TYR182 |
| A | LYS186 |
| A | PRO212 |
| A | ARG22 |
| A | GLY213 |
| A | SER215 |
| A | LEU216 |
| A | MTX1278 |
| A | HOH1291 |
| A | HOH1294 |
| A | HOH1336 |
| A | ILE23 |
| A | ARG43 |
| A | HIS44 |
| A | SER45 |
| A | GLY69 |
| A | ASP70 |
| A | LEU71 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MTX A 1278 |
| Chain | Residue |
| A | ARG22 |
| A | SER103 |
| A | TYR105 |
| A | ASP169 |
| A | LEU176 |
| A | TYR182 |
| A | LEU214 |
| A | LEU216 |
| A | MSE221 |
| A | THR225 |
| A | TYR229 |
| A | NDP1277 |
| A | HOH1331 |
| site_id | AC3 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NDP B 2277 |
| Chain | Residue |
| B | ARG22 |
| B | ILE23 |
| B | TYR42 |
| B | ARG43 |
| B | HIS44 |
| B | SER45 |
| B | GLY69 |
| B | ASP70 |
| B | LEU71 |
| B | SER72 |
| B | ASN101 |
| B | ALA102 |
| B | SER103 |
| B | ALA104 |
| B | LEU167 |
| B | CYS168 |
| B | ASP169 |
| B | TYR182 |
| B | LYS186 |
| B | PRO212 |
| B | GLY213 |
| B | SER215 |
| B | LEU216 |
| B | MTX2278 |
| B | HOH2286 |
| B | HOH2292 |
| B | HOH2293 |
| B | HOH2336 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MTX B 2278 |
| Chain | Residue |
| B | ARG22 |
| B | SER103 |
| B | TYR105 |
| B | ASP169 |
| B | LEU176 |
| B | PHE179 |
| B | TYR182 |
| B | LEU214 |
| B | LEU216 |
| B | MSE221 |
| B | THR225 |
| B | TYR229 |
| B | NDP2277 |
| site_id | AC5 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NDP C 3277 |
| Chain | Residue |
| C | SER215 |
| C | LEU216 |
| C | MTX3278 |
| C | HOH3289 |
| C | HOH3290 |
| C | HOH3291 |
| C | HOH3323 |
| C | HOH3349 |
| C | HOH3373 |
| C | ARG21 |
| C | ARG22 |
| C | ILE23 |
| C | ARG43 |
| C | HIS44 |
| C | SER45 |
| C | GLY69 |
| C | ASP70 |
| C | LEU71 |
| C | SER72 |
| C | ASN101 |
| C | ALA102 |
| C | SER103 |
| C | LEU167 |
| C | CYS168 |
| C | TYR182 |
| C | LYS186 |
| C | PRO212 |
| C | GLY213 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MTX C 3278 |
| Chain | Residue |
| C | ARG22 |
| C | SER103 |
| C | TYR105 |
| C | ASP169 |
| C | LEU176 |
| C | TYR182 |
| C | LEU214 |
| C | LEU216 |
| C | THR225 |
| C | TYR229 |
| C | NDP3277 |
| C | HOH3326 |
| C | HOH3370 |
| site_id | AC7 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NDP D 4277 |
| Chain | Residue |
| D | ARG21 |
| D | ARG22 |
| D | ILE23 |
| D | TYR42 |
| D | ARG43 |
| D | HIS44 |
| D | SER45 |
| D | GLY69 |
| D | ASP70 |
| D | LEU71 |
| D | SER72 |
| D | ASN101 |
| D | ALA102 |
| D | SER103 |
| D | GLU131 |
| D | LEU167 |
| D | CYS168 |
| D | TYR182 |
| D | LYS186 |
| D | PRO212 |
| D | GLY213 |
| D | SER215 |
| D | LEU216 |
| D | MTX4278 |
| D | HOH4286 |
| D | HOH4287 |
| D | HOH4293 |
| D | HOH4317 |
| D | HOH4318 |
| D | HOH4345 |
| D | HOH4381 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE MTX D 4278 |
| Chain | Residue |
| D | ARG22 |
| D | SER103 |
| D | TYR105 |
| D | LEU176 |
| D | PHE179 |
| D | TYR182 |
| D | LEU214 |
| D | LEU216 |
| D | MSE221 |
| D | THR225 |
| D | TYR229 |
| D | NDP4277 |
| D | HOH4313 |
| D | HOH4367 |
| D | HOH4371 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. DamtdlplpgFcvYTMAKHALgGLTrAAA |
| Chain | Residue | Details |
| A | ASP169-ALA197 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| A | PHE179 | |
| A | LYS186 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| B | PHE179 | |
| B | LYS186 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| C | PHE179 | |
| C | LYS186 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| D | PHE179 | |
| D | LYS186 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| A | LYS186 | |
| A | TYR182 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| B | LYS186 | |
| B | TYR182 | |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| C | LYS186 | |
| C | TYR182 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| D | LYS186 | |
| D | TYR182 | |
