1MXF

Crystal Structure of Inhibitor Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	PTERIDINE REDUCTASE 2	polymer	276	29322.0	4	UniProt (Q8I814) Pfam (PF13561)	Trypanosoma cruzi
2	E, G, I, K (A, B, C, D)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	4	Chemie (NDP)
3	F, H, J, L (A, B, C, D)	METHOTREXATE	non-polymer		454.4	4	Chemie (MTX)
4	M, N, O, P (A, B, C, D)	water	water		18.0	346	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	117287.8
Non-Polymers*	Number of molecules	8
	Total formula weight	4799.4
All*	Total formula weight	122087.3

*Water molecules are not included.