1MOX

Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha

1MOX の概要

• エントリーDOI: 10.2210/pdb1mox/pdb
• 関連するPDBエントリー: 1IGR 1M6B 2TGF
• 分子名称: Epidermal Growth Factor Receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming Growth Factor alpha, ... (11 entities in total)
• 機能のキーワード: egfr, receptor, complex, growth factor, transferase-growth factor complex, transferase/growth factor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 127948.54

構造登録者

Garrett, T.P.J.,McKern, N.M.,Lou, M.,Elleman, T.C.,Adams, T.E.,Lovrecz, G.O.,Zhu, H.-J.,Walker, F.,Frenkel, M.J.,Hoyne, P.A.,Jorissen, R.N.,Nice, E.C.,Burgess, A.W.,Ward, C.W. (登録日: 2002-09-10, 公開日: 2003-09-10, 最終更新日: 2020-07-29)

• 主引用文献: Garrett, T.P.J.,McKern, N.M.,Lou, M.,Elleman, T.C.,Adams, T.E.,Lovrecz, G.O.,Zhu, H.-J.,Walker, F.,Frenkel, M.J.,Hoyne, P.A.,Jorissen, R.N.,Nice, E.C.,Burgess, A.W.,Ward, C.W.; Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor alpha; Cell(Cambridge,Mass.), 110:763-773, 2002; PubMed: 12297049; DOI: 10.1016/S0092-8674(02)00940-6

実験手法

X-RAY DIFFRACTION (2.5 Å)