Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase (Fe(II)) complexed with tetrahydrobiopterin and norleucine

Summary for 1MMT
Related1J8T 1J8U 1KW0 1MMK
DescriptorPhenylalanine-4-hydroxylase, FE (II) ION, SULFATE ION, ... (6 entities in total)
Functional Keywordsbasket-arrangement, 13 alpha-helices, 8 beta-strands, ferrous iron, oxidoreductase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight38125.90
Andersen, O.A.,Flatmark, T.,Hough, E. (deposition date: 2002-09-04, release date: 2003-09-04, Last modification date: 2011-07-13)
Primary citationAndersen, O.A.,Flatmark, T.,Hough, E.,Stokka, A.J.
2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding
J.Mol.Biol., 333:747-757, 2003
PubMed: 14568534
DOI: 110.1016/j.jmb.2003.09.004
PDB entries with the same primary citation
Experimental method
Structure validation
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